This is a church of Romanesque origin, built in the 12th century, which has undergone numerous alterations throughout its history. From its original phase, the main façade conserves a doorway under a tiled roof in which sculptural elements can be seen in capitals, corbels, mouldings and metopes. Among the plant and animal representations, the scene of Original Sin in one of the capitals is particularly noteworthy.

At the end of the 15th century, the funerary chapel founded by Pedro Solís was added on the north side in Gothic style. Nearby was the town's cemetery and the free-standing chapel of Nuestra Señora de Las Alas, founded in the first half of the 14th century, which is one of the most representative examples of Proto-Gothic architecture in Asturias.

In the Baroque period, the Chapel of Christ was erected at the opposite end of the village (on the site of a previous chapel dedicated to the Virgin of the Rosary). After suffering the ravages of the Civil War and the loss of considerable movable property, what is the oldest preserved building in the centre of Avilés was transformed on several occasions. The main alteration involved the construction, attached to the polygonal apse, of the outbuildings of the Franciscan convent, which were recently demolished. The Franciscan monks left the church in 2013.

Inside is the tomb of Pedro Menéndez de Avilés, the adelantado of La Florida and founder of the oldest city in the United States of America: St. Augustine. His tomb, as well as the commemorative statue located in the Parque del Muelle, is the work of the sculptor Manuel Garci-González.