The construction of the palace began in 1421. It is currently the seat of the Generalitat Valenciana, the government of the Valencian Community, although throughout the history of Valencia the building has been the seat of the following institutions, after which it has been named: the Casa de la Diputación del General del Reino de Valencia (1421-1705), the Real Audiencia (1750-1923), the Diputación Provincial (1923-1982), the Comité Ejecutivo Popular (1936-1937) and finally, the Generalitat Valenciana (1982-present).

In addition to its political symbolism, it is one of the best examples of Valencian civil architecture of the foral period, with the intervention of the main masters of its time.

The architecture of this building represents a complex mixture of artistic styles ranging from Gothic to Herrerian and Renaissance from various periods. The primitive manor house is Mediterranean Gothic with its open courtyard and cantilevered staircase, with an ogival door on the mezzanine, as on the façade, with lintelled windows on the mezzanine and tri-lobed windows on the main level, as well as in the windows underneath the eaves. The falconry doors and the corners are Renaissance and the windows on the first floor are Classicist. The balustrade crowning the towers is of the Escorial style.

The interior of the palace is accessed through the main door, where there is an uncovered Gothic courtyard with a staircase dating from 1525 that leads to the main floor dating from 1482. There is another staircase that leads to the mezzanine of the tower, which has a rich polychrome coffered ceiling, with a lot of gold, which is why this room is called the golden room, designed by Ginés Linares in 1534 and finished by different painters, Juan de Juanes among them. From the golden room we pass to another smaller room, the work of Mariano Benlliure.

On the main floor we enter under a Gothic arch crowned by a beautiful Renaissance frieze. To the right is the oratory, with an altarpiece from 1606, by Fondestald, in which the patron saints of the three arms of the Kingdom are represented. The brocade frontal and a crucifix by Ribalta are very striking. In the solemn hall of the Cortes, the estates are depicted on the canvases on the walls. The fresco is by Juan Sariñena. The tiles of the magnificent plinth come from Valencian factories that imitated the tiles of Triana and Talavera. More important are the ceiling and the gallery. It was carved in wood by Ginés Linares in 1540 and Gaspar Gregori from 1563 to 1566.

In the corridor or hall of kings there is an interesting gallery of portraits of the kings of Valencia, from James I the Conqueror to Alfonso XIII. This hall rises up above the corridor of beams in the hallway and overlooks the Calle Caballeros through its four large windows divided by fine columns. The construction of the room, begun in 1511, is the work of Joan Monçano. The original coffered ceiling disappeared in the 19th century and was replaced by the present one. This room is currently used for receptions. In the other rooms of the palace, the Diputación de Valencia conserves an extraordinary collection of art that includes major works by the most outstanding Valencian artists. The new tower was built in the 1950s by Luis Albert Ballesteros, who has achieved an intelligent blending of the new with the old. Next to the façade of the original tower to the east, there is a small garden that occupies the site left by the old Casa de la Ciudad.